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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ANLN All Species: 22.42
Human Site: S627 Identified Species: 44.85
UniProt: Q9NQW6 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NQW6 NP_061155.2 1124 124199 S627 V S P E S L V S T P R L E L K
Chimpanzee Pan troglodytes XP_001169875 1125 124324 S628 V S P E S L V S T P R L E L K
Rhesus Macaque Macaca mulatta XP_001103129 1127 124400 S628 I S P E S L V S T P R L E L K
Dog Lupus familis XP_539518 1121 123493 S622 V S P E S L V S S P R L E L K
Cat Felis silvestris
Mouse Mus musculus Q8K298 1121 122775 S622 V S L E N V I S S P P S E L R
Rat Rattus norvegicus XP_225479 975 107264 L518 L S S E D R D L L Y S I D A Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_418836 1121 123757 S622 P E V F V S P S K S V G E D S
Frog Xenopus laevis Q801E2 1116 122812 S619 E S P K A L L S P S N K V A A
Zebra Danio Brachydanio rerio NP_001096146 1153 127336 F660 T S T P A N S F L V K S S T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V4P1 1239 136015 E730 S I C T P I E E H H E M E M D
Honey Bee Apis mellifera XP_624050 1031 115155 S574 K G E I S S S S P K K D E P Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795668 1146 126808 S644 D S C I S A A S S L A P I S L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 96.9 87.8 N.A. 80.3 70.3 N.A. N.A. 63.6 56.4 49 N.A. 23.3 25 N.A. 24.7
Protein Similarity: 100 99.6 98.1 92.1 N.A. 87.1 77.1 N.A. N.A. 77.3 71.7 66.3 N.A. 42.7 44.4 N.A. 43.2
P-Site Identity: 100 100 93.3 93.3 N.A. 46.6 13.3 N.A. N.A. 13.3 26.6 6.6 N.A. 6.6 20 N.A. 20
P-Site Similarity: 100 100 100 100 N.A. 80 33.3 N.A. N.A. 13.3 46.6 20 N.A. 26.6 26.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 17 9 9 0 0 0 9 0 0 17 9 % A
% Cys: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 0 0 0 9 0 9 0 0 0 0 9 9 9 9 % D
% Glu: 9 9 9 50 0 0 9 9 0 0 9 0 67 0 0 % E
% Phe: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 0 9 0 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 9 9 0 0 0 0 0 % H
% Ile: 9 9 0 17 0 9 9 0 0 0 0 9 9 0 0 % I
% Lys: 9 0 0 9 0 0 0 0 9 9 17 9 0 0 34 % K
% Leu: 9 0 9 0 0 42 9 9 17 9 0 34 0 42 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 9 0 9 0 % M
% Asn: 0 0 0 0 9 9 0 0 0 0 9 0 0 0 0 % N
% Pro: 9 0 42 9 9 0 9 0 17 42 9 9 0 9 9 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 9 0 0 0 0 34 0 0 0 9 % R
% Ser: 9 75 9 0 50 17 17 75 25 17 9 17 9 9 9 % S
% Thr: 9 0 9 9 0 0 0 0 25 0 0 0 0 9 0 % T
% Val: 34 0 9 0 9 9 34 0 0 9 9 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _